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Lou Gehrig’s syndrome: Here are the first symptoms of this disease

Lou Gehrig’s disease (ALS): early symptoms

Lou Gehrig’s disease, medically called amyotrophic lateral sclerosis (ALS), is a progressive disease affecting the nerve cells that control voluntary muscles. Early symptoms can be subtle and vary considerably from person to person. CDC+1

Common early signs include:

  • Muscle weakness in one hand, arm, leg, or the neck.

  • Muscle twitching (fasciculations), including in the arms, legs, shoulders, or tongue.

  • Muscle cramps.

  • Stiff or tight muscles (spasticity).

  • Clumsiness with the hands—for example, difficulty buttoning clothes, writing, or turning a key.

  • Tripping or stumbling because of weakness in a leg or foot.

  • Slurred or nasal speech.

  • Difficulty chewing or swallowing. NINDS

In some people, the first symptoms involve the hands or legs (“limb-onset” ALS); in others, speech or swallowing problems appear first (“bulbar-onset” ALS). NINDS

Important

These symptoms do not mean someone has ALS. Muscle twitching, cramps, weakness, and difficulty walking can have many other causes. ALS is uncommon, and diagnosis requires a medical evaluation to distinguish it from other neurological conditions. CDC+1

If weakness is progressively worsening, especially if it’s affecting one limb or causing repeated falls, or if there is new difficulty speaking or swallowing, a neurologist should evaluate it promptly.

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