The claim that there are “eight pills you shouldn’t take” is too broad. Several medications can affect kidney function, but many are safe and beneficial when appropriately prescribed and monitored. The risk often depends on the dose, duration, existing kidney disease, dehydration, and combinations with other medicines. NIDDK+1
Medications that deserve particular caution include:
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Ibuprofen and other NSAIDs
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Naproxen
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Diclofenac
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Indomethacin
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Certain antibiotics, particularly some aminoglycosides
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Lithium, especially with long-term use
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Some ACE inhibitors/ARBs — these can actually protect kidneys long-term, but kidney function and potassium need monitoring, particularly during dehydration or acute illness.
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Certain diuretics (“water pills”) — generally useful medicines, but dehydration or inappropriate dosing can contribute to acute kidney injury. National Kidney Foundation+2
The biggest everyday concern is NSAID painkillers. Ibuprofen, naproxen, and diclofenac can reduce blood flow through the kidneys and increase the risk of acute kidney injury, particularly with high doses, prolonged use, dehydration, heart disease, high blood pressure, or existing kidney disease. NIDDK+1
Don’t stop a prescribed medication simply because you’ve seen a warning online. Ask your doctor or pharmacist to review your medications, particularly if you have kidney disease or take several medicines.
