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A cardiologist warns: these 5 medications increase the risk of heart attack and stroke in older people

There are medications that require extra caution in older adults, but the claim that a particular five medicines universally “cause heart attacks and strokes” would be misleading. The risk depends on the drug, dose, medical condition, and why it is being used.

Examples of medication groups that deserve particular attention include:

  • Some NSAID painkillers such as ibuprofen, naproxen, and diclofenac—especially with prolonged use. They can raise blood pressure and cause kidney problems, and cardiovascular risks are important in people with existing heart disease. PubMed Central (PMC)

  • Certain antipsychotic medicines—in older people with dementia, they are associated with increased stroke and mortality risk and are generally avoided for behavioral symptoms unless specific circumstances apply. PubMed Central (PMC)

  • Some diabetes medicines, particularly sulfonylureas, are flagged in the 2023 AGS Beers Criteria because of concerns about hypoglycemia and cardiovascular outcomes compared with some alternatives. American Academy of Family Physicians

  • Aspirin used for primary prevention in older adults can cause significant bleeding, and current geriatric guidance recommends against routinely initiating it solely to prevent a first cardiovascular event. This is different from aspirin prescribed after a heart attack or stroke, where it may provide important benefit. PubMed Central (PMC)

Don’t stop any prescribed medication abruptly based on a warning like this. If you give me the five medication names from the article or video, I can check each one and explain the actual heart-attack/stroke evidence and the relevant precautions for older adults.

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