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15 Hidden Atorvastatin Side Effects Your Doctor May Not Have Time to Mention (But You Deserve to Know Before Your Next Refill)

The headline “15 hidden side effects” overstates what is known. Atorvastatin is generally well tolerated and is prescribed to lower LDL cholesterol and reduce the risk of heart attack and stroke. Still, it has recognized adverse effects and important interactions. 

15 effects or issues to know about

  1. Muscle aches or soreness

  2. Muscle cramps or spasms

  3. Muscle weakness

  4. Rare rhabdomyolysis — severe muscle breakdown that can damage the kidneys.

  5. Rare immune-mediated necrotizing myopathy — an uncommon autoimmune muscle disorder that can persist after stopping the drug.

  6. Headache

  7. Dizziness

  8. Nausea

  9. Indigestion or abdominal discomfort

  10. Constipation or diarrhea

  11. Sleep problems

  12. Joint or musculoskeletal pain

  13. Increased blood glucose or HbA1c in some people.

  14. Elevated liver enzymes — usually detected through blood testing and often without symptoms.

  15. Rare significant liver injury — jaundice or other symptoms require prompt assessment.

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