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23 Strange Signs Your Kidneys Might Be in Trouble

The headline “23 strange signs your kidneys might be in trouble” needs an important correction: early chronic kidney disease often causes no noticeable symptoms, so a long symptom list can give false reassurance or unnecessary fear. Blood and urine testing are often the only way to detect it early.

Possible signs that deserve medical attention

Some symptoms associated with kidney disease—particularly as it becomes more advanced—include:

  1. Foamy or persistently bubbly urine
  2. Blood or pink/dark-colored urine
  3. Urinating much more or less than usual
  4. Frequently waking at night to urinate
  5. Swelling of the feet, ankles, legs, hands, or face
  6. Puffiness around the eyes, especially in the morning
  7. Persistent tiredness or weakness
  8. Trouble concentrating or thinking clearly
  9. Poor appetite
  10. Nausea or vomiting
  11. Unexplained weight loss
  12. Dry or persistently itchy skin
  13. Muscle cramps
  14. Numbness or tingling
  15. Sleep problems
  16. Shortness of breath
  17. Headaches
  18. Changes in taste, including a metallic or unpleasant taste
  19. Increased or worsening blood pressure
  20. Feeling unusually thirsty
  21. Reduced urine output
  22. Generalized swelling or fluid retention
  23. Confusion, particularly in severe kidney dysfunction.

But none of these signs proves that your kidneys are failing. Many have other possible causes. Conversely, someone can have significant kidney disease without having any of them.

The most useful thing to do

If you have diabetes, high blood pressure, heart disease, or a family history of kidney failure, ask a healthcare professional about kidney screening. Common screening includes a blood test to estimate kidney filtration (eGFR) and a urine test for albumin/protein (uACR).

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