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23 Strange Signs Your Kidneys Might Be in Trouble

23 signs that may be associated with kidney problems

The headline is a little misleading: none of these symptoms alone can diagnose kidney disease, and many have much more common explanations. Early chronic kidney disease (CKD) can cause few or no symptoms, which is why blood and urine testing is important for people at risk.

Some possible signs include:

  1. Swelling in the ankles, feet, legs, hands, or around the eyes

  2. Foamy or unusually bubbly urine, which can occur with excess protein in the urine

  3. Blood in the urine (pink, red, or cola-colored urine)

  4. Urinating more often, especially at night

  5. Producing much less urine than usual

  6. Cloudy or unusually dark urine

  7. Persistent fatigue or weakness

  8. Difficulty concentrating or feeling mentally foggy

  9. Poor appetite

  10. Nausea or vomiting

  11. Unexplained weight loss

  12. Dry, itchy skin

  13. Muscle cramps or twitching

  14. Headaches

  15. Sleep problems

  16. Shortness of breath, particularly when fluid accumulates

  17. High blood pressure that is difficult to control

  18. Puffiness around the eyes, especially in the morning

  19. Metallic taste or unpleasant taste in the mouth

  20. Bad or ammonia-like breath in advanced kidney dysfunction

  21. Changes in skin color or unusually pale skin

  22. Pain in the side or back, which can occur with certain kidney conditions such as stones or infection

  23. Persistent hiccups, particularly in advanced kidney failure

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