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A cardiologist warns: these 5 medications increase the risk of heart attack and stroke in older people

The headline is too broad. There isn’t a universal list of exactly five medications that all older adults should avoid because they cause heart attacks or strokes. Medication risk depends on the drug, dose, duration, existing heart disease, kidney function, and other medicines.

One well-established example is non-aspirin NSAID painkillers such as ibuprofen, naproxen, diclofenac, and similar drugs. The FDA warns that NSAIDs can increase the risk of heart attack and stroke, with risk potentially occurring early in treatment and tending to increase with higher doses and longer use. FDA Access Data+1

Other important considerations include:

  • Aspirin: It can reduce the risk of another heart attack or clot-related stroke in people with established cardiovascular disease, but routine daily aspirin isn’t appropriate for everyone. It also increases bleeding risk, including potentially serious bleeding in the brain or digestive tract. U.S. Food and Drug Administration+1

  • Certain medicines in people with heart failure: NSAIDs/COX-2 inhibitors, pioglitazone, and some other drugs can worsen fluid retention or heart failure and therefore require particular caution. American Geriatrics Society

  • Older adults: Medication interactions and adverse effects become more important with age because changes in kidney and liver function can alter how medicines are processed. U.S. Food and Drug Administration+1

Don’t stop prescribed medication because of a viral headline. If you give me the five medication names from the article, I can check each one and explain the actual heart-attack/stroke evidence, including who is at risk.

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