8 Medicines That Can Harm Your Kidneys When Misused
Your kidneys filter many medicines from the blood. Some medications can reduce kidney blood flow or cause kidney injury, particularly with high doses, prolonged use, dehydration, or existing kidney disease.
1. Ibuprofen
Commonly sold for pain and inflammation. Long-term or high-dose use can increase the risk of kidney injury.
2. Naproxen
Another NSAID that can affect kidney blood flow, particularly in people with kidney disease or when taken for prolonged periods.
3. Diclofenac
This NSAID can also affect kidney function, especially with higher doses or prolonged use.
4. Celecoxib
Although it works somewhat differently from some older NSAIDs, celecoxib can still affect kidney function.
5. Indomethacin
This prescription NSAID can cause kidney problems, particularly in people who already have reduced kidney function.
6. Meloxicam
Another NSAID that may increase the risk of acute kidney injury, especially with higher doses or long-term use.
7. High-Dose Aspirin
Aspirin at higher doses can act like an NSAID and may reduce blood flow to the kidneys. Low-dose aspirin prescribed for heart protection is different and should not be stopped without medical advice.
8. Certain Antibiotics
Some antibiotics can occasionally cause kidney injury or require dose adjustments when kidney function is reduced. Never stop an antibiotic early or avoid one prescribed for you without discussing it with your healthcare professional.
Who Needs Extra Caution?
The risk can be higher if you have chronic kidney disease, heart failure, high blood pressure, dehydration, or are taking certain blood-pressure medicines or diuretics.
