23 possible signs or clues
As kidney disease becomes more advanced, possible symptoms include:
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Swelling of the ankles, feet, legs, hands, or face
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Puffy eyes, especially in the morning
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Foamy or unusually bubbly urine
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Blood or pink/cola-colored urine
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Urinating more often
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Urinating less than usual
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Waking frequently at night to urinate
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Persistent tiredness or low energy
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Difficulty concentrating or “brain fog”
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Trouble sleeping
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Poor appetite
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Nausea
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Vomiting
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Unintentional weight loss
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Persistent itching
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Dry skin
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Muscle cramps
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Muscle weakness
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Numbness or tingling
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Shortness of breath
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High blood pressure
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Changes in taste or an unpleasant/metallic taste
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General fluid retention
