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7 medications that cause severe dementia and profound brain damage

If you’re fact-checking this headline, “7 medications that cause severe dementia and profound brain damage” is not medically accurate. No standard list of seven medications is known to cause severe dementia or permanent brain damage in everyone who takes them.

A safer, evidence-based headline would be:

7 Types of Medications That Can Affect Memory and Thinking
Anticholinergic medicines — some drugs for allergies, bladder problems, depression, and sleep can cause confusion and cognitive impairment, particularly in older adults. Long-term exposure to some strong anticholinergics has been associated with increased dementia risk, although association does not prove that the medication directly causes dementia.
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National Institute on Aging
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Benzodiazepines — medicines used for anxiety or insomnia can cause sedation, confusion, memory problems, falls, and delirium, especially in older adults.
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National Institute on Aging
Certain sleep medicines — sedating medications can worsen confusion and increase fall risk in older people.
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National Institute on Aging
Opioid pain medicines — can cause drowsiness and confusion, particularly at higher doses or when combined with other medicines that affect the brain.
Some antiseizure medicines — depending on the drug and individual, cognitive slowing, drowsiness, or confusion can occur.
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National Institute on Aging
Some antipsychotic medicines — can cause significant sedation and other serious adverse effects in older people with dementia; certain antipsychotics also increase stroke risk.
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Alzheimer’s Society
Combinations of several CNS-active medicines — taking multiple drugs that affect the brain can substantially increase the risk of adverse effects, including problems with thinking, falls, and breathing.
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National Institute on Aging

Important: Never abruptly stop a prescribed medication because of an internet article. Some drugs—including benzodiazepines—can cause dangerous withdrawal if stopped suddenly. A doctor or pharmacist can review the medication list and determine whether a safer alternative or dose adjustment is appropriate.

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