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10 Often Overlooked Metoprolol Side Effects That Deserve More Attention

If you’re looking for the details behind this headline, metoprolol can cause a range of side effects, although many people tolerate it well. The exact effects can vary between metoprolol tartrate and metoprolol succinate and according to dose.

10 often-overlooked metoprolol side effects

  1. Fatigue or unusual tiredness — one of the more commonly reported effects.
  2. Dizziness or lightheadedness — may be related to lowered blood pressure or the drug’s effect on heart rate.
  3. Depressed mood — depression has been reported with metoprolol.
  4. Sleep problems or insomnia — difficulty sleeping and nightmares have been reported.
  5. Vivid dreams or nightmares — these are specifically described in the prescribing information.
  6. Memory problems or confusion — short-term memory loss and mental confusion have been reported.
  7. Cold hands and feet — beta-blockade can affect peripheral circulation.
  8. Sexual difficulties — sexual dysfunction has been reported with beta-blockers, although the frequency and cause can vary.
  9. Diarrhea or other digestive symptoms — diarrhea, nausea, constipation, abdominal discomfort, and heartburn have been reported.
  10. Wheezing or shortness of breath — particularly important for people with asthma or other bronchospastic conditions.

More important warning signs

Metoprolol can also cause slow heart rate, low blood pressure, worsening heart failure, fainting, swelling, or breathing difficulties. It can mask some warning signs of low blood sugar, particularly a rapid heartbeat, which matters for people with diabetes.

Don’t stop metoprolol suddenly. Abrupt withdrawal can cause serious heart problems, including worsening angina or other cardiac complications. Any dose reduction or discontinuation should be planned with the prescribing clinician.

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